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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNRF1 All Species: 13.94
Human Site: S91 Identified Species: 27.88
UniProt: Q8ND25 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8ND25 NP_115644.1 227 23783 S91 R A P G G G G S A S D S T Y A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001109563 278 29893 S91 R A P G G G G S A S D S T Y A
Dog Lupus familis XP_854366 187 20677 S54 L Q W E Q S N S N D Y S S L Y
Cat Felis silvestris
Mouse Mus musculus Q91V17 227 23824 S91 R A P G G G G S T S D S T Y A
Rat Rattus norvegicus XP_002725463 227 23854 S91 R A P G G G G S T S D S T Y A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512110 89 10164
Chicken Gallus gallus XP_418778 146 15603 G13 F N I P H S S G P Y G S Q D S
Frog Xenopus laevis Q66KG7 195 20714 P61 D P P A A A L P F G L Y R A G
Zebra Danio Brachydanio rerio Q6P4U6 215 22857 D83 A G G G S G S D P A H N G N G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572359 303 31946 R167 M Q S Y M Q Q R R T L G D S I
Honey Bee Apis mellifera XP_624991 212 22738 Q80 P D L T S G E Q S S L A S S V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001198564 213 21441 G81 G Q A M N I P G G S G A S R G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 80.9 44.9 N.A. 99.1 98.6 N.A. 31.2 44.4 72.2 82.8 N.A. 37.6 38.7 N.A. 39.2
Protein Similarity: 100 N.A. 80.9 55.9 N.A. 99.1 98.6 N.A. 35.6 53.7 77.9 88.1 N.A. 47.1 50.2 N.A. 52.8
P-Site Identity: 100 N.A. 100 13.3 N.A. 93.3 93.3 N.A. 0 6.6 6.6 13.3 N.A. 0 13.3 N.A. 6.6
P-Site Similarity: 100 N.A. 100 20 N.A. 93.3 93.3 N.A. 0 13.3 6.6 26.6 N.A. 6.6 33.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 34 9 9 9 9 0 0 17 9 0 17 0 9 34 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 0 0 0 0 0 9 0 9 34 0 9 9 0 % D
% Glu: 0 0 0 9 0 0 9 0 0 0 0 0 0 0 0 % E
% Phe: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % F
% Gly: 9 9 9 42 34 50 34 17 9 9 17 9 9 0 25 % G
% His: 0 0 0 0 9 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 0 0 9 0 0 9 0 0 0 0 0 0 0 0 9 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 0 9 0 0 0 9 0 0 0 25 0 0 9 0 % L
% Met: 9 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 9 0 9 0 9 0 0 9 0 9 0 % N
% Pro: 9 9 42 9 0 0 9 9 17 0 0 0 0 0 0 % P
% Gln: 0 25 0 0 9 9 9 9 0 0 0 0 9 0 0 % Q
% Arg: 34 0 0 0 0 0 0 9 9 0 0 0 9 9 0 % R
% Ser: 0 0 9 0 17 17 17 42 9 50 0 50 25 17 9 % S
% Thr: 0 0 0 9 0 0 0 0 17 9 0 0 34 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % V
% Trp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 9 9 9 0 34 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _